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Table 1 Effects of DFE, DPE and coffee on hepatic oxidative stress markers; TBARS (a marker of lipid peroxidation), AOPP (a marker of protein oxidation) and CAT (as enzymatic antioxidant) in CCl4-intoxicated rats. Values are expressed as mean ± SEM

From: The antifibrotic and fibrolytic properties of date fruit extract via modulation of genotoxicity, tissue-inhibitor of metalloproteinases and nuclear factor- kappa B pathway in a rat model of hepatotoxicity

 

TBARS

(nmol/g tissue)

AOPPs

(μmol/L)

CAT

(U/g tissue)

Control

72.4 ± 7.28

69.43 ± 0.44

6.74 ± 0.15

CCl4

158.7 a*** ± 12.1

208.2 a*** ± 10.7

4.23 a*** ± 0.38

DFE+ CCl4

93.17 b*** ± 5.62

114.1 b*** ± 6.13

5.9 b*** ± 0.147

DPE+ CCl4

107.8 b*** ± 6.54

154.3b*** c* ± 10.32

5.2 b**c* ± 0.2

Coffee + CCl4

129.3 b***c* ± 7.9

155.1 b*** c* ± 10.23

5.04 b**c* ± 0.26

  1. ***P < 0.001, **P < 0.01, *P < 0.05
  2. asignificantly different from normal control group; bsignificantly different from CCl4-treated group, csignificantly different from DFE-treated rats