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Fig. 9 | BMC Complementary and Alternative Medicine

Fig. 9

From: The antifibrotic and fibrolytic properties of date fruit extract via modulation of genotoxicity, tissue-inhibitor of metalloproteinases and nuclear factor- kappa B pathway in a rat model of hepatotoxicity

Fig. 9

Light microscopic photomicrographs of liver tissue immunostained with anti NF-κB p65 primary antibody (Scale bar = 50 μm). Panel a represents liver section from control rat showing normal cytoplasmic distribution (curved arrow) with negative immune reactivity in most of nuclei (arrowheads). Only few weak immune positive nuclei (arrows) were observed. Panel b represents liver section of rat intoxicated with CCl4 in which there are focal strong abnormal immune reactivity of most of hepatocytes nuclei (arrows) and deeply stained cytoplasm (curved arrows). Panels c d and e represent liver sections from rat treated with DFE, DPE and coffee, respectively, revealing decreased number of immunostained nuclei of hepatocytes (arrows) where most of nuclei were negatively stained (arrowheads) particularly in DFE-and coffee-treated groups

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