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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: The antifibrotic and fibrolytic properties of date fruit extract via modulation of genotoxicity, tissue-inhibitor of metalloproteinases and nuclear factor- kappa B pathway in a rat model of hepatotoxicity

Fig. 6

Effect of DFE and DPE on fibrolytic markers in CCl4-intoxicated rats. (a): Light microscopic photomicrographs of liver tissue immunostained with MMP-9 primary antibody (Scale bar = 50 μm). Panel a represents liver section from control group showing normal few immune positive cells’ cytoplasm (arrow) while the nuclei are not immunostained. Panel b represents liver section of rat intoxicated with CCl4 in which strong abnormal immune reactivity of most of hepatocytes cytoplasm and nuclei. Panels c d and e represent liver sections from rats treated with DFE, DPE and coffee, respectively revealed, many hepatocytes with strong positive immune reactivity in both cell’ cytoplasm and nuclei especially with coffee-treated group (arrows). (b): Effect of DFE, DPE and coffee on hepatic levels of MMP-9 in CCl4-intoxicated rats. Values are expressed as mean ± SEM. a: significantly different from normal control group. ** P < 0.01

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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