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Table 2 Post-infection AA5, 10, 20 oral administration influence on food intake changes compared to controls

From: Asiatic acid influences parasitaemia reduction and ameliorates malaria anaemia in P. berghei infected Sprague–Dawley male rats

Parameter

Post-infection treatment

Pre-patent (D 3)

Patent/Treatment (D7–12)

Post-treatment (D13- 21)

Food intake (g/100 g)

NIC

12.3 ± 2.3

13 ± 9.0

13.4 ± 1.6

IC

11.5 ± 1.9

6.7 ± 1.3

N/A

30CHQ

12.3 ± 1.8

7.8 ± 2.0

8.6 ± 1.7

5 AA

12.9 ± 1.3

9.8 ± 1.3*#

9.7 ± 1.5*#

10 AA

12.3 ± 1.8

12.9 ± 2*#

13.2 ± 0.72#

20 AA

12.7 ± 1.6

9.2 ± 1.6α*

10.3 ± 1.2#

  1. NIC is non-infected treated control, IC is infected non-treated control and CHQ is chloroquine control (30 mg/kg). Values are presented as means ± SEM, (n = 6 in each group). α,*,#p < 0.05 by comparison with NIC, IC, 30CHQ groups, respectively. NIC non infected treated control, IC infected control, CHQ chloroquine, AA asiatic acid