Treatment with Rhus tripartita extract curtails isoproterenol-elicited cardiotoxicity and oxidative stress in rats

Table 1 Effect of RTSM on serum marker enzymes of control and experimental rats

Treatments	Dose mg/kg	SGOT(U/L)		SGPT(U/L)		GGT(U/L)		ALP(U/L)		LDH(U/L)		CK(U/l)
Treatments	Dose mg/kg	Mean ± SE	% change	Mean ± SE	% change	Mean ± SE	% change	Mean ± SE	% change	Mean ± SE	% change	Mean ± SE	% change
Control		79.00 ± 3.31		30.01 ± 2.44		4.85 ± 0.23		217.16 ± 11.14		106.08 ± 6.45		135.16 ± 5.43
ISO only	85	200.00 ± 5.78***^a		181.00 ± 7.33***^a		13.65 ± 0.33***^a		435.30 ± 10.02***^a		165.66 ± 6.72***^a		227.33 ± 10.18***^a
RTSM+ ISO	250	159.00 ± 6.53***^b	21↓	150.83 ± 4.11**^b	17↓	10.55 ± 0.40***^b	23↓	379.33 ± 13.32*^b	3↓	150.00 ± 4.91^b	9↓	201.50 ± 5.51^b	11↓
RTSM+ ISO	500	154.00 ± 4.01***^b	23↓	140.00 ± 5.57**^b	23↓	9.16 ± 0.25***^b	33↓	350.33 ± 11.42***^b	20↓	139.66 ± 6.19*^b	9↓	185.50 ± 7.34*^b	18↓

All values represent mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001; ANOVA, followed by Dunnett’s multiple comparison test
^aAs compared with normal group
^bAs compared with only ISO only group

ISSN: 2662-7671