In vitro and in vivo bactericidal activity of Tinospora sagittata (Oliv.) Gagnep. var. craveniana (S.Y.Hu) Lo and its main effective component, palmatine, against porcine Helicobacter pylori

Table 2 Results of in vitro bactericidal tests

Drugs	Diameter of zones of inhibition (mm) ± SEM (100 mg)		MIC (μg/mL)		MBC (μg/mL)
Drugs	H. pylori SS1	H. pylori SCYA201401	H. pylori SS1	H. pylori SCYA201401	H. pylori SS1	H. pylori SCYA201401
No-drugs	0	0	-	-	-	-
1 % DMSO	0	0	-	-	-	-
TSG	15.00 ± 0.12	15.48 ± 0.08	6250	6250	6250	6250
Palmatine	22.18 ± 0.00	21.24 ± 0.02	3.12	6.25	3.12	6.25
Clarithromycin	16.12 ± 0.10	23.20 ± 0.12	32	16	32	16

Notes: TSG, Tinospora sagittata (Oliv.) Gagnep. var. craveniana (S.Y.Hu) Lo (TSG), DMSO dimethyl sulfoxide

ISSN: 2662-7671