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Table 3 Lipid parameters

From: The Korean herbal medicine, Do In Seung Gi-Tang, attenuates atherosclerosis via AMPK in high-fat diet-induced ApoE−/− mice

   

DISGT

Statin

 

ND

HFD

300 mg/kg

10 mg/kg

T-chole (mg/dL)

401.86 ± 21.18

1401.71 ± 69.66***

951.43 ± 56.72###

1145.00 ± 75.60#

LDL (mg/dL)

71.86 ± 2.08

368.29 ± 17.88***

244.14 ± 13.48###

316.33 ± 18.48#

HDL (mg/dL)

22.14 ± 1.27

11.71 ± 1.14***

12.57 ± 1.15

13.17 ± 2.71

TG (mg/dL)

34.57 ± 2.51

278.71 ± 16.06***

43.29 ± 13.11###

75.83 ± 2.42###

Glucose (mg/dL)

134.29 ± 4.40

422.71 ± 36.80***

201.29 ± 12.79###

298.50 ± 12.83##

AST (U/L)

50.29 ± 7.06

571.57 ± 22.64***

333.29 ± 25.70###

370.83 ± 12.62###

ALT (U/L)

29.86 ± 1.71

562.43 ± 14.32***

247.86 ± 33.41###

277.00 ± 20.91###

Creatinine (mg/dL)

0.21 ± 0.02

0.35 ± 0.03**

0.17 ± 0.02###

0.25 ± 0.03

  1. Abbreviations: HFD high-fat diet, DISGT Do In Seung Gi-Tang, T-chole total cholesterol, LDL low-density lipoprotein, HDL high-density lipoprotein, TG triglyceride, AST aspartate aminotransferase, ALT alanine aminotransferase
  2. All data represent mean values ± SEM (n = 8)
  3. **p < 0.01, ***p < 0.001, versus ApoE−/− mice without HFD (ND)
  4. #p < 0.05, ##p < 0.01, and ###p < 0.001, versus HFD-fed ApoE−/− mice (HFD)