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Table 6 The effects of extracts on serum hormones and MDA levels in rats

From: Comparative evaluation of the sexual functions and NF-κB and Nrf2 pathways of some aphrodisiac herbal extracts in male rats

Item

Groups

--P--

Control

Sildenafil

Mucuna pruriens

Tribulus terrestris

Ashwagandha

FSH, mIU/ml

0.33 ± 0.22

0.40 ± 0.37

0.31 ± 0.25

0.34 ± 0.39

0.31 ± 0.24

>0.05

LH, mIU/ml

0.22 ± 0.29

0.30 ± 0.23

0.25 ± 0.17

0.24 ± 0.19

0.27 ± 0.19

>0.05

Testosterone, ng/ml

2.27 ± 0.17c

4.14 ± 0.71a

2.57 ± 0.44c

3.99 ± 0.16ab

3.58 ± 0.18b

0.0001

Serum MDA, μmol/L

0.54 ± 0.05a

0.56 ± 0.06a

0.49 ± 0.04b

0.38 ± 0.02c

0.44 ± 0.02b

0.0001

Testis MDA, nmol/g

1.64 ± 0.09ab

1.68 ± 0.09a

1.55 ± 0.06cb

1.45 ± 0.09d

1.51 ± 0.07cd

0.0001

  1. FSH follicle-stimulating hormone, LH luteinizing hormone, MDA malonaldeyhde; Control, no treatment; Sildenafil, rats treated with Sildenafil (5 mg/kg/d); Mucuna, rats treated with Mucuna pruriens (300 mg/kg bw); Tribulus; rats treated with Tribulus terrestris (300 mg/kg bw); Ashwagandha; rats treated with Ashwagandha (300 mg/kg bw). Data are LS means ± SE (n = 7). Different superscripts in the same row (a–c) indicate group mean differences (p < 0.05)