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Table 5 The effects of extracts on serum biochemical parameters in rats

From: Comparative evaluation of the sexual functions and NF-κB and Nrf2 pathways of some aphrodisiac herbal extracts in male rats

Item

Groups

--P--

Control

Sildenafil

Mucuna pruriens

Tribulus terrestris

Ashwagandha

AST, U/L

97.50 ± 8.92

118.86 ± 33.73

99.29 ± 15.85

104.29 ± 21.86

108.51 ± 23.25

>0.05

ALT, U/L

46.67 ± 6.50

59.86 ± 10.48

48.71 ± 6.78

47.71 ± 10.24

50.00 ± 10.05

>0.05

ALP, U/L

204.00 ± 43.32a

202.14 ± 31.02a

161.86 ± 29.29b

215.86 ± 25.58a

202.00 ± 22.03a

0.0349

CK, U/L

531.00 ± 224.85

399.29 ± 292.28

405.86 ± 189.07

226.86 ± 102.12

331.40 ± 44.57

>0.05

Urea, mg/dl

33.00 ± 2.61

36.43 ± 2.07

36.14 ± 5.08

36.00 ± .3.74

36.80 ± 6.18

>0.05

Creatine, mg/dl

0.30 ± 0.03

0.28 ± 0.03

0.28 ± 0.04

0.29 ± 0.02

0.30 ± 0.03

>0.05

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, CK creatine kinase control, no treatment; Sildenafil, rats treated with Sildenafil (5 mg/kg/d); Mucuna, rats treated with Mucuna pruriens (300 mg/kg bw); Tribulus; rats treated with Tribulus terrestris (300 mg/kg bw); Ashwagandha; rats treated with Ashwagandha (300 mg/kg bw). Data are LS means ± SE (n = 7). Different superscripts in the same row (a–c) indicate group mean differences (p < 0.05)