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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Fungal vincristine from Eutypella spp - CrP14 isolated from Catharanthus roseus induces apoptosis in human squamous carcinoma cell line -A431

Fig. 4

Effect of FVCR on loss of mitochondrial membrane potential and ROS. Cells were treated with different concentrations of FVCR for 24 h and subsequently analyzed for. a: Changes in mitochondrial membrane potential in FVCR treated A431 cells as determined by JC-1 staining and detected by flow cytometry analysis. Bar diagram shows the percentage of cells having low mitochondrial membrane potential in the FVCR-treated cells. b: ROS production in FVCR-treated cells using DCFH-DA fluorescent probe followed by flow cytometry. Bar diagram shows the percentage of ROS production levels of FVCR-treated cells in a concentration-dependent manner

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