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Table 1 Expressions of various neurotransmitters, including the frontal cortex, striatum and hippocampus of brain, in mice

From: Ophiocordyceps formosana improves hyperglycemia and depression-like behavior in an STZ-induced diabetic mouse model

Brain Cortex Treatment Neurotransmitter (ng/g brain tissue)
DA DOPAC 5HT 5HIAA Norepinephrine
Frontal Cortex Control 1277.7 ± 332.8b 741.7 ± 115.5b 797.3 ± 72.8a 863.0 ± 47.2a 409.1 ± 107.3c
  STZ-PBS 238.4 ± 27.00.2b 175.9 ± 55.5c 323.3 ± 93.4c 99.7 ± 11.5c 685.6.9 ± 34.4b
  STZ-Rosi 851.5 ± 307.3b 615.3 ± 54.2b 594.5 ± 220.3bc 283.7 ± 39.9b 939.2 ± 81.8a
  STZ-OFE 2343.2 ± 824.4a 1467.4 ± 136.6a 931.1 ± 45.6a 939.5.7 ± 59.8a 861.33 ± 84.4a
Striatum Control 986.8 ± 73.2b 1013.1 ± 101.6ab 936.7 ± 93.8a 863.0.0 ± 47.2b 916.52 ± 49.9a
  STZ-PBS 806.1 ± 138.3 b 681.6 ± 61.2c 583.1 ± 97.4b 481.0 ± 33.9c 613.7 ± 26.2b
  STZ-Rosi 1185.3 ± 423.9b 797.6 ± 103.1bc 613.8 ± 129.7b 491.7 ± 20.2c 731.8 ± 55.9b
  STZ-OFE 2760.7 ± 323.0a 1069.9 ± 120.8a 693.2 ± 96.7ab 716.7 ± 57.1a 679.6 ± 65.7b
Hippocampus Control 288.5 ± 72.8a 111.7 ± 30.5b 1041.9 ± 103.6b 1040.7 ± 71.6a 257.6 ± 63.9c
  STZ-PBS 84.6 ± 5.1bc 129.0 ± 46.9b 620.2 ± 66.2c 219.0 ± 5.9b 423.5 ± 85.8bc
  STZ-Rosi 19.9 ± 6.2c 49.1 ± 28.0bc 864.3 ± 41.0b 185.4 ± 63.2b 702.9 ± 12.1a
  STZ-OFE 255.1 ± 56.3a 317.4 ± 121.3a 1622.7 ± 83.0a 280.8 ± 61.5b 592.2 ± 107.9ab
  1. DA: dopamine; DOPAC: 3,4-dihydroxy phenlactic acid; 5-HT: 5-hydroxytryptamine; 5-H1AA: 5-hydroxy indole acetic acid. One way ANOVA followed by Tukey’s post hoc test was performed for multiple comparisons. Means in a row with different superscripts, such as a, b, c, ab, bc, is significantly different (p <= 0.05). Values are present as mean ± SEM, n = 6 in control group and n = 8 in the ogher groups