Skip to main content

Table 1 Expressions of various neurotransmitters, including the frontal cortex, striatum and hippocampus of brain, in mice

From: Ophiocordyceps formosana improves hyperglycemia and depression-like behavior in an STZ-induced diabetic mouse model

Brain Cortex

Treatment

Neurotransmitter (ng/g brain tissue)

DA

DOPAC

5HT

5HIAA

Norepinephrine

Frontal Cortex

Control

1277.7 ± 332.8b

741.7 ± 115.5b

797.3 ± 72.8a

863.0 ± 47.2a

409.1 ± 107.3c

 

STZ-PBS

238.4 ± 27.00.2b

175.9 ± 55.5c

323.3 ± 93.4c

99.7 ± 11.5c

685.6.9 ± 34.4b

 

STZ-Rosi

851.5 ± 307.3b

615.3 ± 54.2b

594.5 ± 220.3bc

283.7 ± 39.9b

939.2 ± 81.8a

 

STZ-OFE

2343.2 ± 824.4a

1467.4 ± 136.6a

931.1 ± 45.6a

939.5.7 ± 59.8a

861.33 ± 84.4a

Striatum

Control

986.8 ± 73.2b

1013.1 ± 101.6ab

936.7 ± 93.8a

863.0.0 ± 47.2b

916.52 ± 49.9a

 

STZ-PBS

806.1 ± 138.3 b

681.6 ± 61.2c

583.1 ± 97.4b

481.0 ± 33.9c

613.7 ± 26.2b

 

STZ-Rosi

1185.3 ± 423.9b

797.6 ± 103.1bc

613.8 ± 129.7b

491.7 ± 20.2c

731.8 ± 55.9b

 

STZ-OFE

2760.7 ± 323.0a

1069.9 ± 120.8a

693.2 ± 96.7ab

716.7 ± 57.1a

679.6 ± 65.7b

Hippocampus

Control

288.5 ± 72.8a

111.7 ± 30.5b

1041.9 ± 103.6b

1040.7 ± 71.6a

257.6 ± 63.9c

 

STZ-PBS

84.6 ± 5.1bc

129.0 ± 46.9b

620.2 ± 66.2c

219.0 ± 5.9b

423.5 ± 85.8bc

 

STZ-Rosi

19.9 ± 6.2c

49.1 ± 28.0bc

864.3 ± 41.0b

185.4 ± 63.2b

702.9 ± 12.1a

 

STZ-OFE

255.1 ± 56.3a

317.4 ± 121.3a

1622.7 ± 83.0a

280.8 ± 61.5b

592.2 ± 107.9ab

  1. DA: dopamine; DOPAC: 3,4-dihydroxy phenlactic acid; 5-HT: 5-hydroxytryptamine; 5-H1AA: 5-hydroxy indole acetic acid. One way ANOVA followed by Tukey’s post hoc test was performed for multiple comparisons. Means in a row with different superscripts, such as a, b, c, ab, bc, is significantly different (p <= 0.05). Values are present as mean ± SEM, n = 6 in control group and n = 8 in the ogher groups