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Table 2 Normal gastrointestinal transit in mice treated with the 80 % methanol extract of A. remota

From: Antidiarrheal activity of 80 % methanol extract of the aerial part of Ajuga remota Benth (Lamiaceae) in mice

Group (mg/kg)

Mean of the total length of intestine (cm)

Mean of distance traveled by charcoal meal (cm)

Peristaltic index (PI)

(%) Inhibition

Control

57.77 ± 1.09

40.74 ± 1.25

70.51

0.0

Atropine 3

55.96 ± 1.28

18.33 ± 0.56 a***e*

32.76

55.0

MEAR 200

55.71 ± 1.11

37.56 ± 1.51b***c***d***e***

67.43

7.7

MEAR 400

53.58 ± 0.93

26.28 ± 2.15a***b*

49.05

35.5

MEAR 600

54.47 ± 1.17

20.70 ± 1.18a***

38.00

49.2

MEAR 800

55.30 ± 1.21

14.69 ± 0.55a***e***

26.58

63.9

  1. Values are expressed as mean ± SEM.(n = 6 mice) aagainst control, bagainst standard, cagainst 800 MEAR, dagainst 600 MEAR, eagainst 400 MEAR; * P < 0.05, ** p < 0.001, *** p < 0.001. 200, 400, 600 and 800 mg/kg represent doses of MEAR; Control: control group taking 10 ml/kg 2 % tween 80, Atropine : Atropine sulphate 3 mg/kg