Fig. 3

Effects of iridoids glycosids extract from the stem barks Feretia apodanthera on acute 70 mg/kg pentylenetetrazole-induced seizures in mice. Panel (a) latency to the first seizures, panel (b) number of seizure, panel (c) occurence of seizures (%), panel (d) mortality (%). N = 8 animals per dose. Data were analysis by Fisher Exact Test (two-tailed) for comparison of percentages or two-way repeated measures analysis of variance, followed by Newman-Keuls post hoc test for means comparison, ^* P < 0.05, ^** P < 0.01, ^*** P < 0.001, significantly different compared to the vehicle; Clonaz, clonazepam 0.1 mg/kg. IGEFA, iridoids glycosids extract of Feretia apodanthera