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Table 1 The list of 25 IgAN associated proteins

From: A system biology approach to understanding the molecular mechanisms of Gubentongluo decoction acting on IgA Nephropathy

Uniprotein ID

Symbol

Name

Presence in GBTL

O43707

ACTN4

actinin, alpha 4

Yes

O75907

DGAT1

diacylglycerol O-acyltransferase homolog 1

Yes

P00797

REN

Renin

Yes

P01019

AGT

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Yes

P01375

TNF

tumor necrosis factor (TNF superfamily, member 2)

Yes

P04637

TP53

tumor protein p53

Yes

P05412

JUN

jun oncogene

Yes

P11473

VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

Yes

P12268

IMPDH2

IMP (inosine monophosphate) dehydrogenase 2

Yes

P12821

ACE

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Yes

P20839

IMPDH1

IMP (inosine monophosphate) dehydrogenase 1

Yes

P35228

NOS2

nitric oxide synthase 2, inducible

Yes

P49721

PSMB2

proteasome (prosome, macropain) subunit, beta type, 2

Yes

Q00987

MDM2

Mdm2 p53 binding protein homolog (mouse)

Yes

Q96D42

HAVCR1

hepatitis A virus cellular receptor 1

Yes

Q96PD7

DGAT2

diacylglycerol O-acyltransferase homolog 2

Yes

O00151

PDLIM1

PDZ and LIM domain 1

No

P11836

MS4A1

membrane-spanning 4-domains, subfamily A, member 1

No

P20618

PSMB1

proteasome (prosome, macropain) subunit, beta type, 1

No

P28074

PSMB5

proteasome (prosome, macropain) subunit, beta type, 5

No

P35612

ADD2

adducin 2 (beta)

No

P43405

SYK

spleen tyrosine kinase

No

Q13200

PSMD2

proteasome (prosome, macropain) 26S subunit, non-ATPase, 2

No

Q14005

IL16

interleukin 16 (lymphocyte chemoattractant factor)

No

Q99460

PSMD1

proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

No

  1. GBTL indicated the Traditional Chinese Medicine Gubentongluo decoction