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Table 2 Influence of CGA7 complex on weight gain and metabolic variables in HFD- fed rats

From: Biomechanism of chlorogenic acid complex mediated plasma free fatty acid metabolism in rat liver

Parameter

Control

High fat diet

High fat diet + orlistat (30 mg/kg b.w.)

High fat diet + CGA7 (50 mg/kg b.w.)

High fat diet + CGA7 (100 mg/kg b.w.)

High fat diet + CGA7 (150 mg/kg b.w.)

Body weight gain (g)

68.41 ± 1.18

112.0 ± 4.51# # #

88.01 ± 3.68***

75.65 ± 3.44***

65.88 ± 2.14***

60.63 ± 2.89***

Food intake (g/day)

14.93 ± 0.77

8.26 ± 0.51# # #

8.54 ± 0.40

7.78 ± 0.45

8.96 ± 0.45*

6.98 ± 0.35

Liver weight (g)

3.87 ± 0.18

4.50 ± 0.19#

3.47 ± 0.11***

3.56 ± 0.10***

3.57 ± 0.12***

3.39 ± 0.10***

Mesenteric fat (g)

0.59 ± 0.06

1.31 ± 0.12# # #

0.98 ± 0.03*

1.01 ± 0.07*

1.0 ± 0.04*

1.00 ± 0.07*

Epididymal fat (g)

0.58 ± 0.02

2.07 ± 0.12# # #

1.26 ± 0.05*

1.06 ± 0.03***

0.84 ± 0.02***

0.74 ± 0.02**

  1. Data represent the means ± SEM (n = 6). Data were analysed using one way Anova for analysing the differences between groups (#, p < 0.05, # # #, p < 0.001) compared with control group. *, p < 0.05, **, p < 0.01 and ***, p < 0.001 compared with HFD group