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Table 8 Effect of M. buxifolia on biomolecules in renal tissues of rat

From: Protective effects of Monotheca buxifolia fruit on renal toxicity induced by CCl4 in rats

Treatment mg/kg bw

GSH (μM/g tissue)

TBARS (nM/min/mg protein)

H2O2 (μM/ml)

Nitrite (μM/mg protein)

% DNA injuries

Control

32.67 ± 1.22a

3.18 ± 0.62c

1.32 ± 0.27c

105.42 ± 2.10c

8.21 ± 0.53c

CCl4

15.30 ± 1.37d

5.32 ± 0.55a

2.72 ± 0.36a

142.25 ± 2.24a

26.32 ± 1.29a

CCl4 + Sily 50

31.21 ± 1.49b

3.26 ± 0.12c

1.45 ± 0.24c

109.52 ± 2.12c

9.15 ± 0.70c

CCl4 + MBM 200

23.64 ± 2.53c

4.24 ± 0.39b

2.04 ± 0.35b

124.27 ± 2.41b

14.23 ± 0.85b

CCl4 + MBM 400

30.57 ± 2.32b

3.22 ± 0.35c

1.38 ± 0.24c

108.75 ± 2.12c

9.49 ± 0.72c

MBM 400

34.46 ± 2.94a

3.12 ± 0.31c

1.43 ± 0.23c

107.24 ± 2.35c

8.02 ± 0.37c

  1. Values are expressed as mean ± SEM (06). Means ± SEM with different superscript letter (a–d) within the column indicate significant difference (P < 0.05 between a&b, P < 0.01 between a&c, P < 0.001 between a&d), MBM M. buxifolia methanol extract