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Table 2 IC50 values (after 72 h) of the tested plant extracts towards leukemia CCRF-CEM cells and as determined by the resazurin assay

From: Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines

Tested plant

IC50 values (μg/mL)

Alchornea laxiflora roots

>80

Boerhavia diffusa (whole plant)

>80

Combretum hispidum bark

>80

Eremomastax speciosa (whole plant)

>80

Laportea aestuans (whole plant)

>80

Laportea ovalifolia leaves

>80

Laportea ovalifolia roots

>80

Spathodea campanulata leaves

>80

Pennisetum purpureum (whole plant)

69.01 ± 7.99

Spathodea campanulata bark

63.29 ± 8.61

Spathodea campanulata roots

58.08 ± 4.27

Alchornea laxiflora bark

49.21 ± 11.16

Alchornea laxiflora leaves

43.67 ± 4.06

Albizia adianthifolia leaves (AAL)

33.34 ± 3.55

Combretum hispidum leaves

32.05 ± 2.41

Alchornea cordifolia roots (ACR)

27.28 ± 1.22

Alchornea cordifolia bark (ACB)

12.57 ± 0.55

Alchornea cordifolia leaves (ACL)

8.02 ± 0.23

Albizia adianthifolia bark (AAB)

1.45 ± 0.13

Albizia adianthifolia roots (AAR)

0.98 ± 0.08

Doxorubicin

0.11 ± 0.03

  1. In bold: significant cytotoxic effect; Leukemia CCRF-CEM cells were tested in RPMI 1640 medium supplemented with 10 % FBS and 1 % penicillin-streptomycin