Antidiarrheal activity of crude methanolic root extract of Idigofera spicata Forssk.(Fabaceae)

Table 2 Effect of crude hydromethanolic extract of root of Indigofera spicata on castor oil induced diarrhea in mice

Group	Onset of diarrhea (min)	Total number of faeces in 4 h (frequency of defecation in 4 h)	Mean evacuation index	Fluid content of the faces (g)	% Inhibition of diarrhea
NS	63.33 ± 5.58	11.83 ± 1.30	2.39 ± 0.09	0.78 ± 0.13	0.00
3 mg/kg Lop	99.17 ± 18.14	5.83 ± 0.75*	2.29 ± 0.15	0.36 ± 0.05*	51.02
100 mg/kg IS	71.83 ± 5.67	9.17 ± 0.70	2.34 ± 0.06	0.61 ± 0.11	22.49
200 mg/kg IS	75.33 ± 4.86	6.67 ± 1.52*	2.17 ± 0.08	0.32 ± 0.09*	43.62
400 mg/kg IS	121.17 ± 12.18*^ab	5.50 ± 0.67*	1.96 ± 0.16	0.35 ± 0.08*	53.51

Values are mean ± S.E. (n = 6), * for p < 0.05 compared to the negative control, ^a for p < 0.05compared to 100 mg/kg IS and ^b for p < 0.05 compared to 200 mg/kg IS

ISSN: 2662-7671