Effect of β-sitosterol against methyl nitrosourea-induced mammary gland carcinoma in albino rats

Table 1 Effect of MNU and β-sitosterol on differentiation of mammary gland

Groups	AB1	AB2	AB1 + AB2	LOBULES	DF SCORE- 1 (AB1 + AB2 + LOBULES)	DF SCORE 2 (LOBULES/AB1 + AB2)
CONTROL (3 ml/kg)	685.75 ± 223.36	367.75 ± 79.88	1053.5 ± 302.45	1805.75 ± 460.39	2859.25 ± 756.67	1.76 ± 0.09
MNU (47 mg/kg)	786.5 ± 20.56	432.5 ± 36.60	1219 ± 57.17	2606 ± 243.72	3825 ± 300.89	2.13 ± 0.09
β-SITOSTEROL + MNU (10 mg/kg + 47 mg/kg)	532 ± 178.53	201.5 ± 48.64*	733.5 ± 227.17	1774.5 ± 417.74	2508 ± 644.92	2.48 ± 0.19
β-SITOSTEROL + MNU (20 mg/kg + 47 mg/kg)	380.5 ± 111.83	143 ± 2.00**	523.5 ± 113.83	1390.5 ± 142.92	1914 ± 256.76	2.72 ± 0.31

(Values are Mean ± SEM), each group contains eight animals. Comparisons were made on the basis of the one-way Anova followed by Bonferroni test. All groups were compared to the toxic control group (*p < 0.05, **p < 0.01)

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