Evaluation of antioxidant, anti-hemolytic and anticancer activity of various solvent extracts of Acacia hydaspica R. Parker aerial parts

Table 5 Cytotoxic effect of A. hydaspica methanol extract and its derived fractions on MDA-MB 361, HCC-38 and Vero cells of green monkey after 48 h of treatment

Extract/Fraction	MDA361 cell line	SI	HCC38 cell line	SI	Vero cell line
	IC₅₀ (μg/ml)	IC₅₀V/IC₅₀M	IC₅₀ (μg/ml)	IC₅₀V/IC₅₀H	IC₅₀ (μg/ml)
AHM	46.9 ± 1.31*	5.42	75.9 ± 1.32*	3.34	254 ± 1.81
AHE	29.9 ± 0.91*	9.83	39.5 ± 0.87*	7.44	294 ± 1.55
AHB	37.1 ± 1.01*	6.97	56.1 ± 0.93*	4.60	258 ± 1.68

Each value expressed as mean ± SEM (n = 3). Selectivity index (SI) >3 is considered to be highly selective, * shows significance at p <0.001 as compared to Vero cells. M represents MDA-MB-361; V represents Vero and H represents HCC38 cell lines. (One way ANOVA followed by Tukey’s multiple comparison test)

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