Table 1 Assessment of orally-administered SFEE on serum biochemical parameters in rats treated for 28 days
Group I | Group II | Group III | Group IV | Group V | Group VI | Group VII | Group VIII | |
|---|---|---|---|---|---|---|---|---|
Control | 50 mg/kg | 100 mg/kg | 150 /kg | 250 mg/kg | 500 mg/kg | 750 mg/kg | 1000 mg /kg | |
Albumin (mg/dl) | 4.69 ± 0.12 | 4.65 ± 0.1 | 4.72 ± 0.27 | 4.63 ± 0.16 | 5.1 ± 1.2 | 4.53 ± 0.26 | 4.87 ± 0.19 | 4.92 ± 0.19 |
Cholesterol (mg/dl) | 72 ± 3.07 | 73 ± 2.09 | 71 ± 3.6 | 71 ± 3.1 | 72 ± 5.7 | 73 ± 1.2 | 70 ± 1.7 | 74 ± 6.1 |
Bilirubin (mg/dl) | 0.11 ± 0.03 | 0.12 ± 0.01 | 0.11 ± 0.02 | 0.11 ± 0.02 | 0.11 ± 0.02 | 0.13 ± 0.06 | 0.12 ± 0.08 | 0.13 ± 0.01 |
Triglycerides (mg/dl) | 71 ± 2.5 | 72 ± 3.1 | 71 ± 2.3 | 69 ± 1.6 | 73 ± 1.5 | 71 ± 2.1 | 72 ± 3.2 | 73 ± 6.1 |
ALT (U/L) | 42 ± 1.3 | 41 ± 2.3 | 44 ± 3.5 | 42 ± 2.6 | 43 ± 3.6 | 42 ± 3.1 | 44 ± 2.5 | 44 ± 3.1 |
AST (U/L) | 101 ± 2.8 | 101 ± 3.8 | 99 ± 5.2 | 100 ± 3.7 | 102 ± 5.4 | 98 ± 3.8 | 102 ± 5.3 | 103 ± 7.3 |
ALP (U/L) | 24 ± 2.1 | 24 ± 1.57 | 25 ± 1.5 | 24 ± 2.2 | 26 ± 1.2 | 25 ± 1.7 | 25 ± 1.4 | 24. ± 2.2 |
LDH (U/L) | 578 ± 37 | 572 ± 39 | 587 ± 57 | 581 ± 48 | 601 ± 35 | 590 ± 45 | 600 ± 53 | 598 ± 65 |
GSH (μM/100 mg liver) | 5.2 ± 0.87 | 5.2 ± 0.12 | 5.4 ± 0.45 | 5.3 ± 0.58 | 5.4 ± 0.97 | 5.1 ± 0.3 | 5.2 ± 0.4 | 5.23 ± 0.5 |
MDA (n mole/g liver) | 17 ± 2.9 | 18 ± 3.2 | 16 ± 3.8 | 17.2 ± 4.1 | 17 ± 3.5 | 17.8 ± 2.8 | 18 ± 4.8 | 19 ± 3.7 |
Urea (U/L) | 5.1 ± 0.68 | 5.3 ± 0.62 | 5.2 ± 0.76 | 5.2 ± 0.13 | 5.2 ± 0.56 | 5.3 ± 0.4 | 5.13 ± 0.34 | 5.3 ± 0.67 |
Creatinine (mg/dl) | 25 ± 2.3 | 27 ± 2.1 | 25 ± 0.83 | 25 ± 3.1 | 26 ± 0.76 | 26.7 ± 0.7 | 27.1 ± 0.9 | 28.2 ± 3.7 |