From: Acute and chronic toxicities of Bacopa monnieri extract in Sprague-Dawley rats
Hematological parameter | Control | B. monnieri extract | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
30 mg/kg | 60 mg/kg | 300 mg/kg | 1,500 mg/kg | Satellite group | ||||||||||||||
RBC (x106/μl) | 8.96 | ± | 0.27 | 9.03 | ± | 0.37 | 8.80 | ± | 0.13 | 8.56 | ± | 0.20 | 8.98 | ± | 0.18 | 9.92 | ± | 0.20* |
HB (g/dl) | 16.36 | ± | 0.37 | 16.22 | ± | 0.30 | 16.24 | ± | 0.22 | 15.84 | ± | 0.29 | 16.41 | ± | 0.27 | 17.50 | ± | 0.26* |
HCT (%) | 50.00 | ± | 1.60 | 50.80 | ± | 2.12 | 48.80 | ± | 0.73 | 48.60 | ± | 1.05 | 50.20 | ± | 0.89 | 56.60 | ± | 0.98* |
MCV (fl) | 55.70 | ± | 0.30 | 56.10 | ± | 0.43 | 55.40 | ± | 0.27 | 56.50 | ± | 0.31 | 55.80 | ± | 0.59 | 57.00 | ± | 0.30* |
MCH (pg) | 18.30 | ± | 0.22 | 18.09 | ± | 0.44 | 18.41 | ± | 0.25 | 18.56 | ± | 0.27 | 18.30 | ± | 0.31 | 17.61 | ± | 0.13 |
MCHC (g/dl) | 32.83 | ± | 0.45 | 32.18 | ± | 0.79 | 33.13 | ± | 0.38 | 32.82 | ± | 0.37 | 32.75 | ± | 0.38 | 30.90 | ± | 0.17* |
PLT (x105/μl) | 0.83 | ± | 0.05 | 0.85 | ± | 0.05 | 0.77 | ± | 0.02 | 0.73 | ± | 0.02 | 0.72 | ± | 0.09 | 0.68 | ± | 0.04* |
WBC (x103/μl) | 5.18 | ± | 0.34 | 4.96 | ± | 0.38 | 5.87 | ± | 0.36 | 6.32 | ± | 0.61 | 7.03 | ± | 0.63* | 6.27 | ± | 0.67 |
NEU (x103/μl) | 1.37 | ± | 0.16 | 1.28 | ± | 0.15 | 1.30 | ± | 0.14 | 1.53 | ± | 0.42 | 1.41 | ± | 0.19 | 2.03 | ± | 0.26 |
LYMP (x103/μl) | 3.18 | ± | 0.39 | 3.40 | ± | 0.24 | 4.27 | ± | 0.28 | 9.59 | ± | 5.25* | 5.31 | ± | 0.50 | 3.63 | ± | 0.58 |
MONO (x103/μl) | 0.15 | ± | 0.03 | 0.23 | ± | 0.06 | 0.21 | ± | 0.06 | 0.27 | ± | 0.07 | 0.19 | ± | 0.03 | 0.23 | ± | 0.04 |
EOS (x103/μl) | 0.04 | ± | 0.02 | 0.04 | ± | 0.03 | 0.09 | ± | 0.03 | 0.04 | ± | 0.02 | 0.06 | ± | 0.02 | 0.03 | ± | 0.02 |
BASO (x103/μl) | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 | 0.00 | ± | 0.00 |