Skip to main content

Table 3 Organ weight (g) of female rats in chronic toxicity test

From: Acute and chronic toxicities of Bacopa monnieri extract in Sprague-Dawley rats

 

Control

B. monnieri extract

30 mg/kg

60 mg/kg

300 mg/kg

1,500 mg/kg

Satellite group

Brain

1.97

±

0.02

1.94

±

0.03

1.94

±

0.03

2.07

±

0.04*

2.08

±

0.02*

2.01

±

0.03

Lung

2.16

±

0.26

2.16

±

0.26

2.00

±

0.14

2.14

±

0.13

2.32

±

0.19

2.00

±

0.13

Heart

1.27

±

0.05

1.22

±

0.03

1.24

±

0.04

1.38

±

0.09

1.36

±

0.06

1.31

±

0.05

Liver

9.90

±

0.32

9.55

±

0.28

8.71

±

0.30*

9.72

±

0.23

9.33

±

0.29

9.54

±

0.27

Spleen

0.83

±

0.03

0.81

±

0.03

0.74

±

0.03

0.83

±

0.03

0.84

±

0.04

0.79

±

0.04

Pancreas

1.03

±

0.09

1.09

±

0.08

1.21

±

0.14

1.34

±

0.13

1.42

±

0.14*

0.98

±

0.12

Adrenal

0.04

±

0.00

0.04

±

0.00

0.05

±

0.00

0.04

±

0.00

0.04

±

0.00

0.04

±

0.00

kidney

1.27

±

0.02

1.28

±

0.02

1.20

±

0.03

1.22

±

0.02

1.24

±

0.04

1.25

±

0.03

Ovary

0.07

±

0.00

0.08

±

0.00

0.09

±

0.01*

0.09

±

0.01*

0.09

±

0.01*

0.07

±

0.00

Uterus

1.18

±

0.14

1.36

±

0.33

1.01

±

0.07

0.96

±

0.09

0.86

±

0.05

1.13

±

0.10

  1. A satellite group was given the B. monnieri extract at 1,500 mg/kg daily over 270 days followed by no treatment for 28 days
  2. Values are expressed as mean ± S.E.M., n = 10. *Significantly different from control, p < 0.05