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Table 3 Influence of A. podagraria tincture and metformin on plasma values of lipid metabolism in rats receiving dexamethasone; Mean ± S.E.M; Q50 (Q25–Q75), n = 5–6 in each group

From: The influence of goutweed (Aegopodium podagraria L.) tincture and metformin on the carbohydrate and lipid metabolism in dexamethasone-treated rats

  Total cholesterol, mmol/l HDL cholesterol, mmol/l LDL cholesterol, mmol/l VLDL cholesterol, mmol/l Atherogenic index Total lipids, g/l
Intact control 2.38 ± 0.20 2.36 (2.20–2.51) 1.72 ± 0.13 1.64 (1.47–1.93) 0.62 ± 0.05 0.58 (0.57–0.66) 0.20 ± 0.02 0.20 (0.17–0.25) 0.39 ± 0.07 0.44 (0.26–0.50) 2.48 ± 0.18 2.56 (2.10–2.70)
Dexamethasone 2.71 ± 0.30 2.64 (2.20–3.02) 2.03 ± 0.22 2.16 (1.73–2.20) 0.55 ± 0.08 0.59 (0.47–0.59) 0.30 ± 0.04* 0.32 (0.24–0.36) 0.42 ± 0.04 0.42 (0.38–0.45) 2.82 ± 0.23 2.88 (2.61–2.94)
Dexamethasone + metformin, 50 mg/kg 2.62 ± 0.19 2.49 (2.32–2.82) 2.17 ± 0.14 2.20 (1.89–2.29) 0.31 ± 0.10 0.27 (0.23–0.35) 0.30 ± 0.04* 0.28 (0.25–0.34) 0.21 ± 0.06**** 0.23 (0.10–0.25) 2.60 ± 0.26 2.54 (2.13–2.77)
Dexamethasone + A. podagraria tincture, 1 ml/kg 2.80 ± 0.15* 2.76 (2.53–2.84) 2.31 ± 0.18** 2.11 (2.07–2.36) 0.24 ± 0.05***,****, ******* 0.28 (0.18–0.33) 0.24 ± 0.02 0.26 (0.23–0.28) 0.22 ± 0.03*****,****** 0.23 (0.21–0.25) 2.91 ± 0.29 2.79 (2.41–3.16)
Dexamethasone + metformin. 50 mg/kg + A. podagraria tincture, 1 ml/kg 2.92 ± 0.11* 2.87 (2.78–2.92) 2.19 ± 0.06* 2.12 (2.09–2.23) 0.51 ± 0.08 0.43 (0.38–0.66) 0.22 ± 0.03 0.20 (0.16–0.25) 0.33 ± 0.03**** 0.33 (0.28–0.38) 2.61 ± 0.17 2.51 (2.35–2.83)
  1. * – p < 0.05 compared to intact control; ** – p < 0.02 compared to intact control; *** – p < 0.01 compared to intact control
  2. **** – p < 0.05 compared to dexamethasone (untreated); ***** – p < 0.01 compared to dexamethasone (untreated)
  3. ****** – p < 0.05 compared to the group receiving metformin and A. podagraria tincture
  4. ******* – p < 0.02 compared to the group receiving metformin and A. podagraria tincture
  5. Medians are highlighted in bold