Fig. 4

(a) FH ex and (b) SFH ex treatment attenuates UVB-induced MMP and increases TIMP levels in HaCaT cells. Total RNA was extracted from HaCaT cells. mRNA levels of MMP-1, and TIMPs were determined by RT-PCR analysis. Pro-collagen protein levels were determined by western blot analysis. *** P< 0.001, **P < 0.01, *P < 0.05 vs UVB vehicle group