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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Cnidium officinale extract and butylidenephthalide inhibits retinal neovascularization in vitro and in vivo

Fig. 3

The effect of COE on retinal neovascularization in OIR mice. a The retinal blood vessels were visualized via fluorescein angiography using FITC-dextran. Nor, normal control mice; OIR, saline-treated OIR mice and COE, OIR mice treated with 100 mg/kg of COE. b The quantification results are expressed as the percentage of the central nonperfused area within the total retinal area. c The retinal neovascular tufts were visualized using isolectin B4 staining. Nor, normal control mice; OIR, saline-treated OIR mice; COE, OIR mice treated with 100 mg/kg of COE. d The quantification results are expressed as neovascular tufts on the retina surface. The bar graph values represent the mean ± SE (n = 5; *p < 0.05 vs. the saline-treated OIR mice)

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