Fig. 5
From: Chondroprotective and anti-inflammatory effects of ChondroT, a new complex herbal medication
Effects of ChondroT on the production of pro-inflammatory cytokines in LPS-activated RAW264.7 cells. RAW264.7 cells were pretreated with ChondroT for 2 h and then incubated with LPS for 24 h. Inflammatory mediators were measured in the cell supernatants by ELISA. ChondroT decreased the LPS-induced production of IL-1β (a), IL-6 (b), and PGE2 (c). NO in the supernatant was detected by Griess reagent (d). LPS-induced NO production in RAW264.7 cells was decreased by ChondroT treatment. +P < 0.01 and +++P < 0.001 compared with the untreated group. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the LPS-treated group