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Table 3 Effects of the subchronic oral administration of EOs on organ weights in Swiss mice

From: In vivo toxicity and antitumor activity of essential oils extract from agarwood (Aquilaria crassna)

Organ weight (g)

Control

EOs 100 mg/kg

EOs 500 mg/kg

Male

Female

Male

Female

Male

Female

Brain

0.40 ± 0.03

0.45 ± 0.07

0.40 ± 0.02

0.46 ± 0.02

0.40 ± 0.03

0.45 ± 0.03

Heart

0.25 ± 0.02

0.19 ± 0.01

0.24 ± 0.03

0.18 ± 0.01

0.24 ± 0.04

0.19 ± 0.01

Liver

2.36 ± 0.55

2.28 ± 0.55

2.22 ± 0.10

2.56 ± 0.19

2.34 ± 0.08

3.10 ± 0.21*

Spleen

0.25 ± 0.02

0.20 ± 0.02

0.20± 0.02

0.21± 0.02

0.20 ± 0.02

0.23 ± 0.02

Kidney

0.29 ± 0.01

0.32 ± 0.01

0.26 ± 0.1

0.25 ± 0.1

0.24 ± 0.03*

0.23 ± 0.07*

Lungs

0.25 ± 0.02

0.23± 0.02

0.24 ± 0.02

0.22 ± 0.02

0.23 ± 0.02

0.24 ± 0.03

Pancreas

0.30±0.05

0.35±0.04

0.29±0.03

0.36±0.02

0.31±0.04

0.36±0.04

  1. Values are presented as mean ± SD, (*P < 0.05)