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Table 2 Determination of EC50 and CC50 of Cortex phellodendri in RAW264.7, HEK293T and HeLa cells

From: Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo

Cell

Ec50 ± S.D.b(μg/ml)

CC50 ± S.D.c(μg/ml)

PR8-GFP

VSV-GFP

NDV-GFP

H3-GFP

HSV-GFP

EV-71

Raw264.7

0.89 ± 0.09

0.71 ± 0.15

0.57 ± 0.13

-

-

-

7.31 ± 0.12

HEK293T

-

0.63 ± 0.06

-

-

0.83 ± 0.07

-

6.36 ± 0.06

HeLa

-

-

-

0.75 ± 0.12

-

0.39 ± 0.07a

8.06 ± 0.04

  1. aEffective concentration for 50 % reduction in CPE
  2. bEffective concentration for 50 % reduction in GFP expression
  3. cCytotoxic concentration causing 50 % cell death. The results are a mean of three independent experiments