Skip to main content
Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Neuroprotective effects of Paeonia Lactiflora extract against cell death of dopaminergic SH-SY5Y cells is mediated by epigenetic modulation

Fig. 1

Changes of cell viability and mRNA expressions of SOD2 and HMOX1 in MPP+ treated cells. a MPP+ treatment decreased cell viability depending on concentrations of MPP+. b MPP+ treatment decreased mRNA expressions of SOD2 related with clearing mitochondrial ROS. The results confirmed MPP+ induces apoptosis by way of inhibition of mitochondrial complex. c MPP+ treatment increased mRNA expressions of HMOX1 related with the antioxidant pathway. The results consent HMOX1 is induced by oxidative stress.; The data was indicated as the mean ± S.E.M. P < 0.05 was defined statistical significance. One-way ANOVA followed by Duncan post hoc test

Back to article page