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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: The electroacupuncture-induced analgesic effect mediated by 5-HT1, 5-HT3 receptor and muscarinic cholinergic receptors in rat model of collagenase-induced osteoarthritis

Fig. 2

The effects of pretreatment of 5-HT1 receptor agonist (8-OH-DPAT, EA+8 ODT, n = 10) and antagonist (spiroxatrine, EA+SPROX, n = 10) in the CIOA rat treated by 2 Hz EA (EA+DMSO, n = 10) assessed by TFL (a) and PPT (b). Pretreatment with DMSO, 8 ODT, and SPROX was performed 20 min before 2 Hz EA. *p < 0.05, **p < 0.01, ***p < 0.001: compared with EA+DMSO

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