Resistin mediates tomato and broccoli extract effects on glucose homeostasis in high fat diet-induced obesity in rats

Table 4 Effect of tomato and broccoli extract on serum resistin, leptin and adiponectin in HFD induced obesity in rats

Groups	Resistin (ng/ml)	Leptin (Pg/ml)	Adiponectin (Pg/ml)
Control	0.93 ± 0.05	16.3 ± 0.57	120 ± 3.81
HFD	11.2 ± 0.48*	147 ± 3.70*	27.8 ± 0.94*
SD	8.05 ± 0.29^,*	118 ± 4.20^,*	40.2 ± 2.36^,*
T 200	4.13 ± 0.22^,^,**	44.8 ± 2.13^,^,**	95.5 ± 3.84^,^,**
T 400	1.51 ± 0.04^,^,**	22.7 ± 0.84^,^,**	131 ± 3.84^,*
B 200	5.91 ± 0.29^,^,**	80.3 ± 3.14^,^,**	78.5 ± 2.42^,^,**
B 400	2.32 ± 0.15^,^,^,**	41 ± 2.45^,^,^,**	122 ± 3.61^,*
CX	1.37 ± 0.03^,^,^,**	45.7 ± 2.91^,^,^,**	112 ± 4.77^,^,***

Tomato and broccoli extracts treatment at different doses significantly reduced serum resistin and leptin while increased adiponectin levels in HFD rats. C = control; HFD = high fat diet; SD = stop diet; T 200 = tomato extract 200 mg/kg; T 400 = tomato 400 mg/kg; B 200 = broccoli 200 mg/kg; B 400 = broccoli 400 mg/kg; CX = Chromax
*= Significant from control at P < 0.0001, **Significant from HFD at P < 0.0001, ***Significant from SD at P < 0.05, ****Significant from T 400 at P < 0.001. Results were expressed as mean ± SEM and analyzed using one-way ANOVA followed by Bonferroni’s post hoc test

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