Resistin mediates tomato and broccoli extract effects on glucose homeostasis in high fat diet-induced obesity in rats

Table 2 Effect of tomato and broccoli extract on body weight and adipose tissue index in HFD induced obesity in rats

Groups	Initial weight (gm)	Final weight (gm)	% Δ weight (gm)	Adipose tissue index
Control	127 ± 1.59	166 ± 5.4	30.3 ± 2.89	0.82 ± 0.07
HFD	126 ± 1.49	259 ± 6.73	106 ± 5.13*	2.6 ± 0.21*
SD	126 ± 1.31	218 ± 5.36	72.8 ± 4.79^,*	2.21 ± 0.13^,*
T 200	128 ± 1.03	199 ± 7.39	56.1 ± 6.11^,^,**	1.1 ± 0.04^,^,**
T 400	126 ± 1.59	190 ± 4.54	51.6 ± 4.11^,^,**	0.81 ± 0.08^,*
B 200	133 ± 1.06	214 ± 5.68	60.4 ± 4.81^,*	1.47 ± 0.18^,^,**
B 400	132 ± 1.53	211 ± 9.12	59.1 ± 6.45^,*	1.03 ± 0.1^,*
CX	136 ± 1.28	221 ± 4.49	60.2 ± 3.19^,^,**	1.58 ± 0.27^,*

Tomato and broccoli extracts treatment at different doses significantly reduced body weight and adipose tissue index in HFD rats. C = control; HFD = high fat diet; SD = stop diet; T 200 = tomato extract 200 mg/kg; T 400 = tomato 400 mg/kg; B 200 = broccoli 200 mg/kg; B 400 = broccoli 400 mg/kg; CX = Chromax. Results were expressed as mean ± SEM and analyzed using one-way ANOVA followed by Bonferroni’s post hoc test. * = Significant from control at P < 0.0001, **= Significant from HFD at P < 0.0001, *** = Significant from SD at P < 0.05. Results were expressed as mean ± SEM and analyzed using one-way ANOVA followed by Bonferroni’s post hoc test

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