Fig. 3From: Anti-allodynic effect of intrathecal processed Aconitum jaluense is associated with the inhibition of microglial activation and P2X7 receptor expression in spinal corda Changes in P2X7 receptor (P2X7R) expression in the spinal cord ipsilateral to the SNL by Western blot analysis. Bar graphs depicting the relative intensity of P2X7R expression show a gradual increase in P2X7R levels in the ipsilateral dorsal spinal cord. b Effect of intrathecal (i.t.) administration of PA on P2X7R expression in the ipsilateral dorsal spinal cord. Representative blots showing the expression of P2X7R and GAPDH on day 7 following SNL. Intrathecal injection of PA or saline was performed from days 3 to 7. The increase in P2X7R in the ipsilateral dorsal spinal cord was significantly blocked in animals treated with i.t. PA (300 μg). N = 7 per group. *P < 0.05 vs. naiveBack to article page