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Table 2 Characteristics and clinical findings of 10 MP cases

From: Total dosage of gardenia fruit used by patients with mesenteric phlebosclerosis

No. Age Sex

Chief complaint/MP symptom

Kampo formulas containing GF/Clinical findings

GF intake cumulative dosage Administration period

Pre-existing disease

1. 76 M

Chief complaint Hypertension

Orengedokuto

15,792 g 14.1 years

DM, HT, LDL-c

MP symptom none

Clinical findings (location) Colonoscopy: Bronze coloration (C to T) Redness and Erosion (C to A) Histology: Moderate fibrillization CT scan: Linear calcification (C to T) Wall thickening (C to A)

2. 76 M

Chief complaint Hypertension

Orengedokuto, Orengedokuto, Ryutansyakanto

14,683 g 15.9 years

HT, LDL-c

MP symptom none

Clinical findings (location) Colonoscopy: Bronze coloration (C to T) Histology: Severe fibrillization CT scan: Linear calcification (C to T) Wall thickening (C to A)

3. 70 M

Chief complaint Hypertension

Orengedokuto, Kamisyoyosan, Ryutansyakanto, Seihaito

8,119 g 11.9 years

DM, HT, TG

MP symptom Ileus (Colectomy)

Clinical findings (location) Histology: Fibrillization of the colonic mucosa and the mesenteric vein in excision sample CT scan: Linear calcification (C to T) Wall thickening (C to A)

4. 49 F

Chief complaint Skin itching

Unseiin, Kamisyoyosan, Keigairengyoto, Orengedokuto

7,972 g 12.2 years

LDL-c

MP symptom none

Clinical findings (location) Colonoscopy: Mild blue coloration (C to A) Decreased transparency of blood vessels (C to A) Histology: Mild fibrillization CT scan: Slight calcification, CT value increase, Mild vasodilation (the ileocecal vein)

5. 75 M

Chief complaint Cutaneous pruritus

Unseiin

6,579 g 6.8 years

HT

MP symptom Constipation Abdominal pain

Clinical findings (location) Colonoscopy: Dark blue coloration (C to T) Redness and Erosion (C to A) Histology: Severe fibrillization CT scan: Linear calcification (C to T) Wall thickening (C to T)

6. 58 F

Chief complaint Dermatitis and Obesity

Bofutsusyosan, Unseiin, Keigairengyoto, Orengedokuto

6,499 g 13.5 years

LDL-c

MP symptom none

Clinical findings (location) Colonoscopy: Edematous membrane and Bronze coloration (C to A) Histology: Concentric fibrillization surrounding capillary vessel

7. 68 M

Chief complaint Cutaneous pruritus

Unseiin

6,372 g 12.2 years

DM, HT, LDL-c, TG

MP symptom none

Clinical findings (location) Colonoscopy: Bronze coloration (C to T) Histology: Severe fibrillization CT scan: Linear calcification (the ileocolic vein)

8. 58 F

Chief complaint Hot flush

Kamisyoyosan, Kamikihito, Orengedokuto, Shin’iseihaito

5,588 g 4.0 years

LDL-c, TG

MP symptom none

Clinical findings (location) Colonoscopy: Bronze coloration (C to T) Histology: Mild - Moderate fibrillization CT scan: Slight calcification and CT value increase (C to A)

9. 64 F

Chief complaint Flushed face, Feeling of cold

Kamisyoyosan

5,408 g 11.4 years

HT, LDL-c, TG

MP symptom none

Clinical findings (location) Colonoscopy: Mild blue coloration (C to T) Histology: Mild - Moderate fibrillization CT scan: Linear calcification (C to A)

10. 67 F

Chief complaint Hepatitis

Orengedokuto

5,379 g 9.4 years

Liver disease

MP symptom none

Clinical findings (location) Colonoscopy: Mild blue coloration (C to T) Histology: Mild - Moderate fibrillization CT scan: Linear calcification (C to T) Wall thickening (C to A)

  1. CT computed tomography, GF gardenia fruit, MP mesenteric phlebosclerosis, DM diabetes mellitus, HT hypertension, LDL-c elevated low-density lipoprotein cholesterol, TG elevated triglyceride, C the caecum, A the ascending colon, T the transverse colon, Oblique type medicines, traditional decocted herbal medicines
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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