Fig. 4From: RETRACTED ARTICLE: Herbal formula GAPT prevents beta amyloid deposition induced Ca2+/Calmodulin-dependent protein kinase II and Ca2+/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I miceExpression of CaMKII (Average OD) in hippocampal CA1 region in the experimental mice at the age of 11 months old were measured by immunohistochemistry staining. Notes:▲ p < 0.05, ▲▲ p < 0.01,vs control group, *p < 0.05, **p < 0.01,vs model group, ANOVA. Control: C57BL/6 J mice; APP: APPV717I mice; APP + D: donepezil; APP + Gl: GAPT low dose; APP + Gm: GAPT middle dose; APP + Gh: GAPT high dose. CaMKII expression was determined by immunohistochemistry in the hippocampus of experimental mice. Data are expressed as mean ± SD (Average OD) of the CaMKII positive neuronal area (anti-body for CaMKII, 1:1000)Back to article page