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Table 4 Protective outcome of ASME on biochemical parameters in rat kidney

From: Proficiencies of Artemisia scoparia against CCl4 induced DNA damages and renal toxicity in rat

Treatment

Proteins (μg/mg tissue)

GSH (μM/g tissue)

TBARS (nM/min/mgprotein)

H2O2

(μM/ml)

Nitrite

(μM/ml)

Control

2.41 ± 0.16

19.30 ± 1.35

22.35 ± 2.22

0.26 ± 0.02

51.97 ± 3.11

Olive oil + DMSO

2.55 ± 0.09

18.51 ± 2.03

22.08 ± 1.85

0.24 ± 0.02

50.41 ± 3.04

CCl4

1.06 ± 0.10ab

3.75 ± 0.25ab

44.52 ± 3.58ab

0.62 ± 0.02ab

91.74 ± 3.84ab

CCl4 + Sily (100)

2.43 ± 0.14c

18.36 ± 1.64c

23.55 ± 2.16

0.26 ± 0.02bc

52.61 ± 3.16

CCl4 + ASM (150)

1.68 ± 0.18b

09.45 ± 0.94a

25.45 ± 1.43

0.42 ± 0.02bc

54.12 ± 3.05

CCl4 + ASM (300)

2.14 ± 0.12

14.25 ± 1.25

22.96 ± 1.80c

0.31 ± 0.04

52.85 ± 3.03

ASM (300)

2.30 ± 0.17

17.83 ± 1.19c

22.33 ± 1.83c

0.30 ± 0.02

51.49 ± 2.74c

  1. Mean ± SD (n = 6), Sily: Silymirin; ASM: A. scoparia methanol extract. Means with letter “a” indicate significant difference from control, “b” from vehicle control and “c” from CCl4 treated group according to Kruskal-Wallis test at P < 0.05