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Table 1 Protective effects of ASM on comet parameters in renal cells

From: Proficiencies of Artemisia scoparia against CCl4 induced DNA damages and renal toxicity in rat

Group

Comet length (μm)

Head length (μm)

Tail length (μm)

% DNA in head

% DNA in tail

Tail moment (μm)

Control

41.48 ± 2.63

35.04 ± 1.81

6.61 ± 1.03

91.33 ± 2.21

9.53 ± 1.13

0.51 ± 0.031

Olive oil + DMSO

40.85 ± 2.39

34.58 ± 1.78

6.36 ± 0.68

90.36 ± 2.43

10.11 ± 1.04

0.61 ± 0.023

CCl4

63.16 ± 2.11aab

23.29 ± 1.50ab

39.21 ± 2.81ab

74.81 ± 2.18ab

25.28 ± 1.40ab

0.64 ± 0.019

CCl4 + Sily (100)

41.54 ± 2.56c

34.94 ± 2.06c

6.35 ± 0.71c

90.46 ± 2.52c

9.70 ± 1.19bc

0.44 ± 0.021c

CCl4 + ASM (150)

46.76 ± 1.74

28.22 ± 2.21

18.78 ± 1.62

84.53 ± 2.32

15.95 ± 1.42

0.60 ± 0.025

CCl4 + ASM (300)

40.80 ± 2.60c

34.70 ± 2.21c

7.43 ± 1.24c

88.03 ± 2.27c

11.66 ± 1.45c

0.45 ± 0.018c

ASM (300)

43.20 ± 3.21

34.67 ± 2.23c

9.26 ± 1.57c

89.98 ± 1.95c

10.35 ± 1.16c

0.11 ± 0.024bc

  1. Values are expressed as mean ± SD (n = 6), Sily. Silymarin; ASM: A. scoparia methanol extract. Means with letter “a” indicate significant difference from control, “b” from vehicle control and “c” from CCl4 treated group according to Kruskal-Wallis test at P < 0.05