Efficacy of cinnamon bark oil and cinnamaldehyde on anti-multidrug resistant Pseudomonas aeruginosa and the synergistic effects in combination with other antimicrobial agents

Table 2 Antimicrobial susceptibility of 30 clinically isolated MDR-PA strains against currently used antibiotics

Antibiotics	MIC range	MIC50	MIC90	% susceptibility
Antibiotics	(μg/ml)	(μg/ml)	(μg/ml)	S	I	R
Colistin	2–8	4	8	23.3	63.4	13.3
Meropenem	1–1024	16	64	3.3	6.7	90
Imipenem	2–512	16	32	ND	16.7	83.3
Doripenem	0.5–256	4–8	16	3.3	43.3	53.4
Ciprofloxacin	0.5–128	64	128	10	ND	90
Piperacilin	2–1024	256	1024	36.7	ND	63.3
Ceftazidime	2– > 2048	>2048	>2048	6.7	3.3	90

MIC range MIC values from lowest to highest, MIC50 MIC is position of percentile 50, MIC90 MIC is position of percentile 90, S sensitive, COL (≤2 μg/ml), MEM (≤2 μg/ml), IMI (≤2 μg/ml), DOR (≤2 μg/ml), CIP (≤1 μg/ml), PIP (≤16 μg/ml), and CAZ (≤8 μg/ml), I intermediate, COL (4 μg/ml), MEM (4 μg/ml), IMI (4 μg/ml), DOR (4 μg/ml), CIP (2 μg/ml), PIP

ISSN: 2662-7671