Fig. 3From: Rhodiola crenulata extract regulates hepatic glycogen and lipid metabolism via activation of the AMPK pathwayEffects of RCE on TG content and expression of lipogenic enzymes in HepG2 cells. HepG2 cells were cultured in high-glucose (33 mM) medium containing Ins (100 nM) with or without the indicated concentration of RCE (μg/mL) or AICAR (2 mM). Lipogenesis (a), relative protein levels SREBP1and C/EBP (b), and gene expression (e and f) were measured. A quantitative analysis of the protein levels of SREBP1 (c) and C/EBP (d) was conducted. The results represent the mean ± SEM (n = 3), ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. the sample without RCEBack to article page