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Table 1 The mean ± S.D and percentage changes of the four measured parameters in brain homogenates of PPA-acute and sub-acuteintoxicated rats and pollen-treated rats in comparisonwiththecontrol animals

From: Therapeutic potency of bee pollen against biochemical autistic features induced through acute and sub-acute neurotoxicity of orally administered propionic acid

Parameter

Group

N

Mean ± S.D.

Percent change

P value*

P value**

IF ϒ (pg/100 mg)

Control

6

82.82 ± 7.52

100.00

  

PPA-acute

6

123.05 ± 6.58

148.57

0.001

PPA-sub-acute

6

102.60 ± 5.08

123.87

0.001

0.001

Pollen

6

87.40 ± 2.09

105.52

0.203

0.001

Nor-adrenaline (ng/100 mg)

Control

6

4.92 ± 0.61

100.00

  

PPA-acute

6

3.25 ± 0.36

66.12

0.001

PPA-sub-acute

6

2.88 ± 0.32

58.49

0.001

0.086

Pollen

6

3.79 ± 0.15

77.18

0.005

0.013

5-HT (ng/100 mg)

Control

6

6.20 ± 0.78

100.00

  

PPA-acute

6

3.78 ± 0.56

61.00

0.001

PPA-sub-acute

6

3.11 ± 0.18

50.07

0.001

0.029

Pollen

6

4.36 ± 0.42

70.36

0.005

0.069

Dopamine (ng/100 mg)

Control

6

21.12 ± 2.72

100.00

  

PPA-acute

6

13.69 ± 0.80

64.81

0.001

PPA-sub-acute

6

11.17 ± 1.29

52.92

0.001

0.002

Pollen

6

16.09 ± 0.71

76.20

0.005

0.001

Caspase 3 (u/100 mg)

Control

6

112.66 ± 4.20

100.00

  

PPA-acute

6

134.79 ± 3.27

119.65

0.001

PPA-sub-acute

6

152.57 ± 8.97

135.43

0.001

0.003

Pollen

6

124.23 ± 2.89

110.28

0.001

0.001

  1. *P value between control group and other groups
  2. **P value between PPA-acute group and other groups