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Table 5 Effect of essential oil on BSA denaturation inhibitory activity, percentage inhibition compared to sodium diclofenac

From: Chemical composition, in vitro antioxidant and anti-inflammatory properties of essential oils of four dietary and medicinal plants from Cameroon

  A. cepa A. sativum D. gossweileri P. brazzeana Diclofenac sodium
Concentration (μg/ml) Inhibition percentage (%)
 3.125 7.33 ± 1.15b 4.00 ± 0.00a 4.00 ± 0.00a 7.56 ± 2.00b 7.33 ± 0.00b
 6.25 9.33 ± 1.15a 6.00 ± 2.00a 8.67 ± 2.31a 16.477 ± 1.15b 9.33 ± 1.15a
 12.5 14.00 ± 2.00a 14.00 ± 2.00a 13.33 ± 3.05a 26.94 ± 2.00b 14.00 ± 0.00a
 25 33.33 ± 1.15c 22.66 ± 2.30b 19.33 ± 1.15a 38.95 ± 1.15d 18.00 ± 0.00b
 50 54.67 ± 3.05c 38.00 ± 2.00b 28.00 ± 2.00a 52.52 ± 1.15c 24.00 ± 0.00a
 75 82 ± 1.04e 57 ± 1.08c 42 ± 0.11b 72.87 ± 0.98d 36 ± 2.00a
 100 - 76 ± 0.91c 56 ± 0.76b - 48 ± 1.00a
 125 - 95 ± 1.02c 70 ± 2.14b - 60 ± 1.73a
Regression curve equations y = 1.070x + 2.579 y = 0.753x – 3.637 y = 0.525x + 3.642 y = 0.907x + 8.587 y = 0.430x + 5.090
R2 = 0.991 R2 = 0.976 R2 = 0.991 R2 = 0.973 R2 = 0.982
IC50 value (μg/mL) 44.31 61.577 88.30 45.66 104.44
  1. Linear regression analysis was used to calculate IC50 value
  2. Values followed by the same superscript letter (a, b, c, d or e) within the same line are not significantly different (p > 0.05) according to Tukey’s HSD test