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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy

Fig. 3

CD44 inhibition reduced invasiveness, migration and the ability of wound healing in MCF7/C6 cells. a siRNA transfection knocks down CD44 expression in MCF7/C6 cells. Left: Western blot showing the inhibition of CD44 in MCF7/C6 cells after transfection of siRNA-CD44 for 48 h; Right: Flow cytometry analysis showing the decrease of cell fractions with CD44-positive expression in MCF7/C6 cells with transfection of siRNA-CD44. b Representative images for cancer cell invasion, migration and wound-healing assays in MCF7/C6 cells with or without CD44 inhibition. c Quantitation of invasiveness, migration and wound healing ability in MCF7/C6 cells with CD44 inhibition. Data represent the average from at least three independent experiments. *Indicates statistical significance (p < 0.05)

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