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Table 1 The total polyphenol content and EC50 of α-amylase and α-glucosidase activity of fractions of F. lutea extract

From: Antidiabetic activity of the ethyl acetate fraction of Ficus lutea (Moraceae) leaf extract: comparison of an in vitro assay with an in vivo obese mouse model

Fractions aTotal polyphenol (mg GAE/g dry weight extract) aα-Amylase inhibition (EC50) μg/ml aα-Glucosidase inhibition (EC50) μg/ml
Hexane 14.86 ± 1.43b ˃1000 ˃1000
Chloroform 10.32 ± 0.82b ˃1000 ˃1000
Dichloromethane 11.83 ± 2.32b ˃1000 854.51 ± 56.92c
Ethyl acetate 100.51 ± 1.60c 39.53 ± 7.10c 126.78 ± 30.62e
n-Butanol 79.58 ± 0.50d 26.50 ± 1.22d 195.17 ± 63.60d
Water 13.34 ± 0.85b ˃1000 558.40 ± 51.67c
fAcarbose - 7.71 ± 0.42b 6.28 ± 0.03b
  1. aValues are means of triplicate determinations done three times (n = 9) ± standard error;
  2. b,c,d,eNo significant difference between extracts with same value, but significant difference p ˂ 0.05 between different values
  3. fPositive control for α-amylase and α-glucosidase