Fig. 8
From: Cycloartanes from Oxyanthus pallidus and derivatives with analgesic activities
Time-dependant acute (panel a) effect of Pallidioside B (OP5) and Pallidioside C (OP6) and repeated treatment of OP5 (panel b) on inflammation induced by formalin (2 %, 100 μl) injection in rat paw. Animals were orally treated with different compounds and injected one hour later with formalin. The diameter of the paw was measured before treatment and after formalin injection. For chronic experiment, animals were daily treated and the diameter of the paw was measured before drug administration. Each point represents the mean ± SEM, n = 8. *P < 0.05, **p < 0.01, ***p < 0.001 significant differences compared to the control. Diclo: diclofenac