Fig. 3
Effects of kinsenoside on mRNA expression of the inflammatory cytokines, MMP-9 and MCP-1 in the joints of CIA mice. Fragments were amplified by RT-PCR (a). The expression levels of IL-1β, TNF-α, IL-10, MMP-9 and mRNA were measured and quantified densitometrically (b). The mice were treated as described in the Materials and methods section. Values were expressed as means ± SD, n = 6 in each group. # P < 0.05, ## P < 0.01 as compared with the naïve group. * P < 0.05, ** P < 0.01 as compared with the H2O-treated group