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Table 4 Effects of Clinacanthus nutans extracts on serum insulin resistance biomarkers in high fat and high cholesterol-fed rats after 7 weeks of intervention

From: Effects of phenolic-rich extracts of Clinacanthus nutans on high fat and high cholesterol diet-induced insulin resistance

Groups

 

Insulin resistance biomarkers

Insulin

(ng/ml)

Glucose

(mmol/l)

HUMAN-IR

RBP4

(ng/ml)

Adiponectin

(ng/ml)

Leptin

(ng/ml)

NC

1.23 ± 0.09a

4.42 ± 0.34a

5.12 ± 1.12a

25.00 ± 1.72a

88.76 ± 16.86a

7.02 ± 0.81a

HFHC

2.97 ± 0.12b

6.20 ± 0.22b

17.36 ± 3.11b

56.50 ± 1.96b

41.54 ± 02.41b

3.21 ± 1.12b

STATIN

2.54 ± 0.11c

5.45 ± 1.26b

13.05 ± 2.09b

54.10 ± 4.26b

203.63 ± 07.43c

8.35 ± 0.92a

AL (H)

1.54 ± 0.09d

4.95 ± 0.36a

7.19 ± 1.51a

30.00 ± 7.32a

134.25 ± 05.50d

12.00 ± 0.41c

AL (M)

1.92 ± 0.12e

5.38 ± 0.57a

9.73 ± 1.29c

35.20 ± 6.68a

83.25 ± 11.11a

8.13 ± 0.51a

AL (L)

2.34 ± 0.10f

5.83 ± 0.22b

12.79 ± 1.90b

47.30 ± 12.32b

63.15 ± 06.07a

5.86 ± 1.24a

MULTI (H)

1.82 ± 0.10e

5.27 ± 0.44a

9.05 ± 1.51c

32.50 ± 8.32a

82.90 ± 21.20a

13.01 ± 1.01c

MULTI (M)

2.51 ± 0.12f

5.44 ± 0.12c

12.87 ± 1.43b

45.20 ± 2.28c

52.06 ± 22.40a,b

8.59 ± 0.73a

MULTI (L)

2.83 ± 0.21g

5.75 ± 0.32 b, c

15.34 ± 1.12b

50.40 ± 1.07b

69.25 ± 15.87a,b

6.43 ± 0.92a

  1. Values represent means ± SD (n = 7/group). Different superscript letters in each column indicate statistical difference (p < 0.05) according to Duncan’s multiple range tests. Groupings are the same as Fig. 1