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Table 5 Human acetycholinesterase inhibitory activity of 20 Korean, Australian, Brazilian, and Chinese propolis ethanol extracts and three commercial anti-Alzheimer’s disease agents

From: Relationship between total phenolic contents and biological properties of propolis from 20 different regions in South Korea

Sample

IC50, μg/mL (95 % CL)

Slope ± SE

χ2a

P-value

P1

70.0 (56.9–86.1)

1.0 ± 0.12

7.33

0.9113

P2

15.6 (11.2–21.6)

0.6 ± 0.05

3.04

0.9321

P3

55.7 (44.7–69.4)

1.1 ± 0.14

7.71

0.9018

P4

47.9 (39.0–59.0)

1.1 ± 0.14

6.96

0.9128

P5

119.9 (98.2–146.4)

2.4 ± 0.48

12.2

0.9066

P6

89.8 (80.1–100.6)

2.2 ± 0.23

6.75

0.9685

P7

48.0 (40.8–56.55)

1.2 ± 0.12

5.88

0.9406

P8

79.3 (72.6–86.6)

4.8 ± 0.67

6.67

0.9760

P9

103.2 (91.8–116.1)

2.6 ± 0.33

7.56

0.9665

P10

104.2 (89.2–121.7)

2.0 ± 0.26

8.59

0.9459

P11

123.4 (115.1–132.2)

2.6 ± 0.20

4.49

0.9878

P12

61.6 (56.4–67.2)

2.5 ± 0.25

5.57

0.9724

P13

101.6 (84.8–121.7)

2.0 ± 0.32

10.29

0.9242

P14

102.1 (84.8–122.8)

1.8 ± 0.26

9.87

0.9245

P15

104.9 (85.6–128.6)

1.8 ± 0.30

11.04

0.9070

P16

33.9 (26.5–43.2)

1.1 ± 0.13

6.39

0.9012

P17

130.8 (122.5–139.6)

4.1 ± 0.60

5.58

0.9842

P18

124.8 (101.7–153.2)

1.6 ± 0.22

9.94

0.9094

P19

327.3 (297.7–359.7)

2.6 ± 0.26

6.04

0.9785

P20

26.7 (20.7–34.5)

0.9 ± 0.09

4.85

0.9213

Australian

242.9 (231.9–254.5)

3.2 ± 0.22

3.39

0.9940

Brazilian

147.0 (139.4–155.1)

2.9 ± 0.19

3.66

0.9930

Chinese

230.9 (208.7–255.5)

3.6 ± 0.62

7.88

0.9696

Tacrine

1.2 (0.9–1.6)

0.4 ± 0.02

3.87

0.9712

Huperzine A

0.2 (0.1–0.3)

0.4 ± 0.03

5.33

0.9246

DH

0.4 (0.3–0.6)

0.3 ± 0.02

4.78

0.9466

  1. DH donepezil hydrochloride
  2. aPearson’s chi-square goodness-of-fit test