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Table 2 Effect of the drug treatments on the relative organ weight, disease activity index, macroscopic scoring and serum biochemical parameters in indomethacin induced CD in rats

From: Emu oil offers protection in Crohn’s disease model in rats

 

Macroscopic scoring

ROW

DAI (g/cm)

Group

day 6

day 9

day 6

day 9

day 6

day 9

Control

-

-

0.033a ± 0.008

0.033a ± 0.001

0.063a ± 0.0013

0.061a ± 0.0016

Indomethacin

2.20d ± 0.20

1.43b ± 0.20

0.054b ± 0.002

0.056d ± 0.001

0.092b ± 0.003

0.082b ± 0.0017

Sulfasalazine

2.00cd ± 0.32

0.71a ± 0.36

0.037a ± 0.003

0.041bc ± 0.001

0.0681a ± 0.0013

0.063a ± 0.0027

Aloe vera

1.60bcd ± 0.25

0.50a ± 0.22

0.048ab ± 0.0006

0.049c ± 0.0021

0.067ab ± 0.0047

0.064a ± 0.0016

Emu oil

1.00abc ± 0.32

Nil

0.045ab ± 0.004

0.039ab ± 0.003

0.067a ± 0.0033

0.064a ± 0.0032

Aloe vera and emu oil combination

0.60a ± 0.25

Nil

0.041ab ± 0.0024

0.042bc ± 0.001

0.077ab ± 0.0062

0.063a ± 0.0045

 

Day 6

Day 9

Group

Cholesterol (mg/dL)

ALP (U/L)

Cholesterol (mg/dL)

ALP (U/L)

Control

63.24a ± 2.14

103.23a ± 1.01

68.45a ± 6.58

106.77a ± 12.37

Indomethacin

61.74a ± 3.045

272.28c ± 25.18

49.80a ± 5.42

274.33c ± 11.74

Sulfasalazine

50.69a ± 9.23

182.67b ± 23.76

52.36a ± 1.53

224.40bc ± 17.81

Aloe vera

61.28a ± 9.27

182.66b ± 8.71

62.38a ± 4.22

169.05abc ± 41.01

Emu oil

57.75a ± 7.30

138.54ab ± 8.12

64.35a ± 4.65

153.50ab ± 21.45

Aloe vera and emu oil combination

56.44a ± 9.48

177.32b ± 20.09

54.98a ± 8.44

154.60ab ± 29.65

  1. All the values were expressed as Mean ± S.E. (n = 6) and means bearing different superscripts in a column differ significantly