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Fig. 7 | BMC Complementary and Alternative Medicine

Fig. 7

From: Allium hookeri root protects oxidative stress-induced inflammatory responses and β-cell damage in pancreas of streptozotocin-induced diabetic rats

Fig. 7

Predicted mechanism in pancreatic tissue on administering AH. Our study revealed that AHR suppresses STZ-induced type 1 diabetes. An important mechanism of AHR’s anti-diabetic effect is its capacity to reduce the oxidative stress state by diminishing ROS generation and lipid peroxidation in the pancreas. Our data further suggest that another critical mechanism of AHR’s anti-diabetic property is its ability to ameliorate inflammation through modulation of the serum TNF-α and IL-6 levels and the pancreatic protein expressions of NF-кB

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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